Maxime Billick, a recent ID staff graduate set to pursue a Master of Public Health at Harvard, and Isaac Bogoch, an infectious diseases physician at the University of Toronto, dive deep into innovative HIV prevention strategies. They explore the buffet of options available, focusing on PrEP, PEP, and the emerging PIP strategy. The conversation addresses the nuances of personalized risk assessment and the importance of tailored strategies for at-risk populations, especially young men. Their insights shed light on the evolving landscape of HIV prevention.