In this engaging discussion, Ashima Makol, M.B.B.S., a rheumatology specialist, and Matthew J. Koster, M.D., who focuses on rheumatologic conditions, tackle the complexities of diagnosing these often elusive disorders. They break down the significance of tests like rheumatoid factor and ANA, discussing when they're actually useful. The duo highlights the potential pitfalls of false positives and negatives, emphasizing the importance of correlating lab results with patient symptoms. They also touch on innovative treatment options emerging in the field.