Dr. Matthew Campbell, an expert on the blood-brain barrier (BBB), joins to unravel its crucial role in health and disease. He discusses how the BBB operates and its manipulation to improve drug delivery for neurological conditions. The conversation dives into the effects of long COVID, highlighting its connection to cognitive decline and brain fog due to BBB disruptions. Dr. Campbell also shares exciting advancements in therapies aimed at repairing the BBB and enhancing cerebrovascular health, blending serious science with a touch of humor.