Omolade Awodu from the University of Benin discusses the latest clinical trials in hemophilia, spotlighting innovative treatments like Consissimab and Fiti Suran. Radek Kaczmarek from Indiana University delves into the advancements in gene therapies, including the use of adeno-associated viral vectors and challenges in delivering transgenes. Matteo Luciani shares insights on the hurdles patients face, emphasizing the need for long-lasting solutions to improve treatment adherence, especially for young children.