Matt DeBurgelis, CTO at Apollo GraphQL, dives into the transformative world of API orchestration. He highlights the advantages of using GraphQL over traditional REST APIs, emphasizing its declarative approach for better integration. The discussion covers the evolution of APIs and the rise of typed languages like TypeScript, showcasing how GraphQL optimizes data retrieval. Additionally, Matt reveals how GraphQL enhances user experience with nullable responses and strong typing, all while addressing the complexities of modern software development involving multiple microservices.