Marlis Gnirke

Marlis Gnirke, a toxicologist and assistant professor at NYU Bellevue, dives deep into the complexities of acetaminophen toxicity. She highlights the surprising presence of acetaminophen in various over-the-counter products, leading to unintentional overdoses. Gnirke discusses the formation of the toxic metabolite NAPQI and its devastating effects on the liver. The conversation also touches on the pivotal role of N-acetylcysteine (NAC) as an antidote and introduces the Rumack-Matthew Nomogram for effective treatment planning.