Mark Ruffalo, actor with humble beginnings and a unique style, discusses his background as a bartender, his passion for climate change, and his personal experience with a brain tumor. The hosts also chat about their fears of turbulence, the impact of the TV show 'Will and Grace', and the acting abilities of an incredible actor.

Mark Ruffalo discusses his dual identity, fear of SNL, health scare, and recent testimony to Congress. The episode also delves into his family history, struggles with dyslexia, and dreams for creative inspiration.

Mark Ruffalo, an Oscar-nominated actor famous for his roles in Spotlight and as the Incredible Hulk, discusses his diverse career and recent role in the dark comedy Poor Things. He shares insights into transitioning to comedic acting and the complexities of his character. Ruffalo opens up about his battle with a brain tumor and how it reshaped his life, reflecting on emotional vulnerability. He also delves into maintaining anonymity in bustling New York City, sharing humorous tips for blending in.

Emma Stone, Willem Dafoe, Mark Ruffalo, and Ramy Youssef discuss their experiences working on 'Poor Things', including set design challenges and unexpected offers. They also explore the complexities of their characters, navigating British accents, and dancing through absurdity in comedic scenes.

Explore reflections on childhood experiences and the impact of films, collaboration with actors, financial management tips, emotional highs and lows of the Oscars, challenges of dialects and character creation, struggles and uniqueness of dyslexia in memorizing scripts, Canadian comedy talent, visual aesthetics in film creation, themes of love and betrayal, music evolution, and home-based music creation.