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Manali Nigam
Editorial fellow at the New England Journal of Medicine and neurologist at Mass General Brigham, participating as the episode's guest editor and clinical discussant.
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51 snips
Dec 10, 2025
• 22min
#195 Antibiotic Duration & BALANCE Trial: Beyond Journal Club with NEJM Group
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Dr. Manali Nigam, an editorial fellow at the New England Journal of Medicine and neurologist at Mass General Brigham, dives into the complexities of antibiotic duration for bacteremia. They dissect the BALANCE trial, revealing how host, organism, and infection source affect treatment courses. Discover why seven days may often suffice, while situations like S. aureus or osteomyelitis demand longer therapy. With a focus on evidence-based practice, Nigam emphasizes the importance of tailored treatment plans despite the push for shorter defaults.
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