Hugh Pym, BBC Health Editor, discusses the unusual early flu surge this season, highlighting hospital pressures and data insights. Dr. Jamie Lopez Bernal, an epidemiologist, explains rapid viral evolution, vaccine effectiveness, and who needs vaccination most. Meanwhile, Lucy Hockings reports from Oslo on María Corina Machado's emotional journey to receive her Nobel Peace Prize, amidst political tensions in Venezuela. Vanessa Buschschlüter adds context about US actions against Maduro and Machado's crucial role in Venezuelan politics.