Luciano Costa
Myeloma physician and researcher at the University of Alabama at Birmingham, specializing in multiple myeloma clinical trials and translational research; presented long-term CARTITUDE-4 cilta-cel outcomes at ASH 2025.
Best podcasts with Luciano Costa
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Dec 11, 2025 • 5min
ASH 2025 | CARTITUDE-4: Long-term PFS outcomes with cilta-cel for standard-risk RRMM
Luciano Costa, a myeloma physician and researcher from the University of Alabama at Birmingham, dives into the fascinating long-term outcomes of the CARTITUDE-4 trial featuring cilta-cel for standard-risk relapsed/refractory multiple myeloma. He highlights how approximately 71% of patients remain progression-free at 30 months and discusses the promising implications for standard-risk patients. Costa also underscores the significant rates of minimal residual disease negativity and speculates that cilta-cel could become a one-time curative option for some, transforming treatment paradigms.
Sep 8, 2023 • 11min
Applications of MRD in multiple myeloma: using MRD to guide treatment decisions
Meral Beksac and Luciano Costa discuss the applications of MRD in multiple myeloma and its potential to guide treatment decisions. They delve into the importance of achieving and sustaining MRD negativity for better patient outcomes. They also explore the impact of maintenance therapy and the potential of using MRD as a surrogate marker in clinical trials to accelerate drug development.
