Join Clarel Antoine, a seasoned obstetrician-gynecologist with a focus on cesarean safety, Yalda Afshar, a physician scientist at UCLA studying the cardiac placental axis, and Lisa Zuckerwise, guest editor on placenta accreta spectrum, for a dive into innovative surgical techniques. They discuss the importance of uterine environment in placentation, explore impactful closure techniques to minimize surgical complications, and emphasize the need for updated guidelines and collaborative research to improve patient outcomes.