Melanie, a passionate researcher on diuretics, joins heart failure expert Craig Brater, who has contributed significantly to the field. They dive into the vital role of diuretics in managing conditions like heart failure and the complexities of dosing strategies. Lety shares innovative methods for estimating furosemide doses based on creatinine levels, emphasizing more accurate formulas over traditional ones. The discussion also touches on sodium intake's impact on treatment efficacy and the intriguing link between sleep apnea and nocturnal urination challenges.