Leanne Williams, a Professor of Psychiatry at Stanford and a leading expert on depression, discusses the condition as a legitimate illness rather than a flaw. She delves into the challenges of traditional treatment methods, highlighting the trial-and-error process many face. The conversation covers exciting advancements in brain mapping and the potential of personalized treatments using biotypes. Williams also emphasizes the role of genetics and AI in reshaping our understanding and treatment of depression, paving the way for innovative therapies.