Andrew Petrosoniak discusses the complexities of using vasopressors in trauma resuscitation. Megan Landes talks about implementing HIV PEP and PrEP in emergency settings, tackling challenges and risk assessments. Justin Morgenstern and George Kovacs delve into the PREOXI trial, shedding light on innovative pre-oxygenation techniques. Brit Long focuses on blast crisis management in leukemia patients, while Leah Flanagan and Liam Loughrey address the rising concerns of nitrous oxide toxicity in recreational users. A blend of critical insights awaits!