
Kristen Dams-O'Connor
Clinician-scientist in neurology and rehabilitation at Icahn School of Medicine at Mount Sinai focused on long-term outcomes after traumatic brain injury and post-traumatic neurodegeneration; lead investigator on the LETBI study discussed in the episode.
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Dec 4, 2025 • 28min
Traumatic Encephalopathy Syndrome in the LETBI Study Cohort
Dr. Kristen Dams-O'Connor, a clinician-scientist at the Icahn School of Medicine, explores traumatic encephalopathy syndrome (TES) linked to traumatic brain injuries. She discusses the long-term outcomes of TBI and clarifies the distinction between clinical features of TES and pathologies like CTE. Kristen outlines her research in the LETBI cohort, highlighting that about 34% of participants met TES core criteria even without repetitive head impacts. She emphasizes the need for improved diagnostics and a multidisciplinary approach to treatment.


