London Breed, former mayor of San Francisco, dives into the city's ongoing challenges, emphasizing homelessness and crime while sharing personal resilience stories. Koleman Strumpf, an economist, humorously navigates the complexities of illicit markets like sports betting and cannabis, and contrasts traditional polling with prediction markets. Erik Brynjolfsson discusses the potential of AI as a human-centered tool, advocating for technology that enhances rather than replaces human ability. It's a dynamic conversation interweaving urban struggles and economic insights.