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Kiran Musunuru

Cardiologist, professor of medicine, and director of the Genetic and Epigenetic Origins of Disease Program at the Perelman School of Medicine, University of Pennsylvania. His research focuses on the genetic basis of heart disease and the development of new therapies.

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Feb 20, 2025 • 30min

Silencing the Genes of a Killer?—Understanding the Heart (Disease) of the Matter

Kiran Musunuru, a renowned cardiologist and professor at the University of Pennsylvania, discusses revolutionary advancements in heart disease treatment. He emphasizes heart disease as a primary global health threat and reveals how CRISPR technology may enable targeted therapies that lower cholesterol permanently. The conversation touches on gene editing's potential to cure severe conditions like sickle cell disease and the importance of clinical trials in safely implementing these innovative treatments. Musunuru's insights illuminate a hopeful future for combating this leading killer.