The podcast discusses Kanna, a South African succulent used by the KhoiSan people for dancing ceremonies and hunting. They explore its history, dosing, and serotonergic activity. The podcast also covers sublingual administration, pharmacokinetics, and pro-social benefits of Kanna. Topics include cultivating Kanna, cutting and dosing tablets, neurotransmitter synthesis, and cultural significance. They touch on supercritical coriander and holy basil extracts, and personalizing supplement stacks.