Ken Stedman, a biology professor at Portland State University, dives into the intriguing world of undiscovered viruses, revealing groundbreaking findings about their diversity in extreme environments. Shiraz Shah, a senior researcher at Copenhagen University Hospital, unveils the surprising connection between gut viruses in infancy and the risk of childhood asthma. Together, they explore the vast viral ecosystems within us and how these little-known agents can significantly shape our health, challenging existing ideas about our microbiome.