Nabarun Dasgupta, a street drug scientist with two decades in overdose prevention, joins Kaylee McLeod, director of Philadelphia's overdose response unit, and Aneri Patani, a senior correspondent focusing on mental health and addiction. They discuss the recent 27% drop in overdose deaths, attributed to public health initiatives and naloxone accessibility. The conversation dives into federal funding challenges, demographic disparities in overdoses, and effective harm reduction strategies, emphasizing the need for empathy and community support in tackling the ongoing crisis.