Kathryn Polkoff

Co-founder and CEO of Hoofprint Biome, a biotech startup using enzymes to reprogram a cow's microbiome. She has a background in animal science and experience with gene editing in cattle.

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Jun 25, 2025 • 22min

How one biotech startup is betting on cows and winning over investors

Kathryn Polkoff, Co-founder and CEO of Hoofprint Biome, dives into an innovative approach to combating climate change by reprogramming cow microbiomes with enzymes. She reveals how this breakthrough can significantly reduce methane emissions and improve feed efficiency. Kathryn shares insights on her journey through animal science, emphasizing the unique perspective of thinking like a farmer. With a recent $15 million funding boost, her startup is blending AI and biology to create a sustainable future for livestock and our planet.

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