Justin E. Juskewitch, M.D., Ph.D., a transfusion medicine expert at the Mayo Clinic, discusses the crucial role of blood donation. He reveals that over 4.5 million lives are saved annually through blood transfusions while only 5% of eligible donors participate. The conversation explores the challenges of donor eligibility, including health assessments and iron deficiencies. Juskewitch emphasizes the importance of primary care clinicians in advocating for donations and highlights community involvement, showcasing how collective action can strengthen the blood supply.