Jonathan Lass

Professor of ophthalmology at Case Western Reserve University and corresponding author for the Diabetes Endothelial Keratoplasty Study, discussing findings on donor diabetes and DMEK outcomes.

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Oct 17, 2025 • 17min

JAMA Ophthalmology : Diabetes in the Donor and Descemet Membrane Endothelial Keratoplasty Success at 1 Year

In this engaging discussion, Dr. Jonathan Lass, a professor at Case Western Reserve University and leading researcher on the Diabetes Endothelial Keratoplasty Study, delves into the effects of donor diabetes on DMEK outcomes. He explains the rising popularity of DMEK, the key role of hemoglobin A1c in classifying donor diabetes, and the trial's impressive success rates—96% for non-diabetic and 97% for diabetic donors. Dr. Lass also shares insights on preparation failures and offers reassurances for surgeons regarding graft outcomes.

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