John Kastelein, M.D.

John Kastelein, a distinguished expert in lipoprotein metabolism and cardiovascular disease, discusses familial hypercholesterolemia (FH) and its genetic underpinnings. He explores innovative therapeutic options that could transform heart disease prevention, detailing the history and future of CETP inhibitors. Kastelein also delves into the APOE gene's significant role in both Alzheimer's and cardiovascular health. His insights emphasize the potential for targeted interventions, sparking optimism for high-risk patients in the near future.