Dr. JoAnn Lindenfeld, Director of Heart Failure at Vanderbilt Heart and Vascular Institute, joins fellows Richa Gupta and Jessica Huston for a deep dive into heart transplantation. They explore the intricacies of organ allocation and recipient selection, stressing the need for equitable processes. The discussion also highlights innovative strategies to expand the donor pool, including using hepatitis C positive hearts. Additionally, the team navigates the critical challenges post-surgery, covering the importance of immunosuppressive medications and long-term care strategies.