Jennifer Rampling, an expert on Renaissance alchemy, discusses alchemical practices in 16th century England, including its sponsorship by Queen Elizabeth I and William Cecil. She explores the process of citrination, the fusion of ideas between quintessence and Ficino's spiritus Mundi, and the defense against accusations of ritual magic. Rampling also delves into the relationship between alchemy and philosophy, the influence of Paracelsus, and the phenomenon of darkness becoming bright in alchemy.