Dr. Jeff Healey, a pioneer in ventricular arrhythmias research, and Dr. Roderick Tung, an expert in arrhythmia management, delve into the VANISH2 trial's crucial findings. They discuss the effectiveness of catheter ablation versus antiarrhythmic drugs for patients with ischemic cardiomyopathy. The conversation highlights the trial's impact on treatment choices and patient outcomes, emphasizing the importance of tailored interventions. Additionally, they explore the complexities of managing non-ischemic cardiomyopathy and address safety considerations in arrhythmia therapies.