In this engaging discussion, Nephrologists Pedro Teixeira, an expert in clinical trials from the University of New Mexico, and Jay Koyner from the University of Chicago dive into the intriguing role of amino acids in managing acute kidney injury (AKI). They unpack recent clinical trials and explore the complexities of kidney function assessments. The conversation also touches on the relationship between amino acids and renal functional reserve, and the comparison with SGLT2 inhibitors in AKI prevention. Expect insightful analysis and practical implications for patient care!