In this podcast, the hosts discuss penicillin allergy, drug allergy de-labelling, and the development of the PEN-FAST tool with insights from Prof Jason Trubiano. They highlight the consequences of mislabeled penicillin allergies, debunk myths surrounding penicillin allergies, and emphasize the importance of investigating allergy histories. The discussion also touches on research on vaccination allergy, COVID-19 vaccine outcomes, and the role of allergists in addressing concerns.