Dr. Akiko Iwasaki, Francisco Gomez-Rivera, and Dr. Jason Augustine talk about the upcoming IMMUNOLOGY2024 meeting. They discuss key sessions to attend, what they’re looking forward to, and offer advice for attendees. Other topics include streptococcus and gastric cancer, targeting senescent cells to prevent aging, and protein complexes and autoimmunity in mice. They also discuss the shrinking Y chromosome, collaboration in immunology, and insights in managing long COVID.