Janine Sengstack

Chief Scientific Officer and co-founder of Junevity, a company developing siRNA therapeutics to treat age-related diseases.

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Apr 2, 2025 • 37min

Cell Reset Therapeutics to Extend Healthspan and Lifespan (Janine Sengstack, Junevity)

Janine Sengstack, Chief Scientific Officer and co-founder of Junevity, discusses innovative siRNA therapeutics aimed at treating age-related diseases. She delves into her research at UCSF that led to the development of the Reset platform, which targets transcription factors to 'reset' aging cells back to health. Janine explains the role of AI in identifying these key factors and the ambition behind Junevity's plans for human clinical trials by 2026, aiming to tackle conditions like diabetes and obesity while extending healthspan and lifespan.