In this enlightening discussion, Dr. Akash Deep, a pediatric intensive care expert from King's College Hospital, and Dr. James Squires, a specialist in pediatric hepatology from UPMC, dive into the complex world of pediatric liver transplants. They explore critical factors influencing transplant eligibility for children with acute liver failure, emphasizing a multidisciplinary approach. Ethical dilemmas, contraindications, and the balance between technical feasibility and patient prognosis are key topics, shedding light on the intricate decision-making processes in this life-saving field.