
James Diggans
Vice President at Twist Bioscience and Chair of the Board for the International Gene Synthesis Consortium, responsible for nucleic acid synthesis biosecurity practices and industry-level screening measures.
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Oct 6, 2025 • 52min
Ideas: More AI-resilient biosecurity with the Paraphrase Project
Microsoft’s Eric Horvitz and guests Bruce Wittmann, Tessa Alexanian, and James Diggans discuss the Paraphrase Project—a red-teaming effort that exposed and secured a biosecurity vulnerability in AI-driven protein design. The work offers a model for addressing AI’s dual-use risks.Show notes