Howard Kornfeld, a renowned pain medicine expert and addiction specialist, discusses the promise of buprenorphine as a treatment for both addiction and chronic pain, comparing it to MDMA. He shares insights on the historical context and potential of ketamine, while also warning about its risks. Kornfeld provocatively connects psychedelics to nuclear disarmament, citing their ability to change minds and promote peace. The conversation emphasizes the need for innovative research and responsible use of psychedelics in addressing global challenges.