Dr. Hanover Matz, a Postdoctoral Fellow at the University of Maryland specializing in comparative immunology, dives into the fascinating immune systems of sharks. He explains how sharks have evolved unique adaptive immune responses and the role of T cells and antibodies. Matz also discusses the innovative work at aquaculture centers, where they immunize nurse sharks, revealing the potential medical applications of shark-derived antibodies. The conversation highlights the surprising complexities of shark immunity compared to mammals, offering intriguing insights into future research.