

Guido Appenzeller
a16z Infrastructure partner who discusses AI-enabled developer tooling, agent orchestration, and the emerging AI software development stack; contributes technical and market insights on AI coding.
Top 5 podcasts with Guido Appenzeller
Ranked by the Snipd community

1,113 snips
Sep 22, 2025 • 1h 40min
Dylan Patel on the AI Chip Race - NVIDIA, Intel & the US Government vs. China
In this enlightening discussion, Dylan Patel, a semiconductor expert and chief analyst at SemiAnalysis, joins Guido Appenzeller, former CTO of Intel’s Data Center, to unpack the shocking $5B NVIDIA-Intel partnership. They explore how this collaboration can impact the AI chip landscape, analyze U.S.-China tech dynamics, and discuss NVIDIA's strategic positioning against competitors like AMD. Insights into data centers and the evolving AI infrastructure reveal the critical hardware choices shaping the future of AI technology.

1,082 snips
May 22, 2025 • 36min
What Is an AI Agent?
Guido Appenzeller, a General Partner at a16z, along with partners Matt Bornstein and Yoko Li, tackle the hot topic of AI agents. They discuss the varying definitions and complexities surrounding these agents, questioning if they are merely enhanced LLMs or something more. The conversation dives into how AI agents are reshaping workplace productivity and the intricate challenges of pricing and integrating them into existing workflows. Ultimately, they envision a future where AI agents are as essential as electricity, transforming our daily lives.

359 snips
Dec 9, 2025 • 38min
The $3 Trillion AI Coding Opportunity
Guido Appenzeller and Yoko Li, partners at a16z, delve into the transformative potential of AI coding, which could reshape the software landscape into a $3 trillion market. They discuss how development roles are evolving as AI disrupts traditional processes. Key topics include the rapid ROI of legacy code migration, AI's versatility in coding languages, and the necessity for new tools and abstractions for agents. Finally, they offer insights for founders on innovating developer workflows and treating AI agents as active users.

264 snips
May 16, 2025 • 45min
Who's Coding Now? AI and the Future of Software Development
Guido Appenzeller, an Infra partner at a16z and a computer science expert, joins fellow partner Matt Bornstein, an AI application specialist, to explore how generative AI is revolutionizing software development. They discuss the rise of 'prompt-based programming' and its impact on developer productivity. The duo delves into the permanence of formal programming languages amidst AI advancements and the complexities of integrating AI into enterprise systems. They also touch on how these changes will reshape coding education and the future landscape of technology.

66 snips
Aug 2, 2023 • 22min
Chasing Silicon: The Race for GPUs
Guido Appenzeller, a seasoned infrastructure expert and former CTO at Intel’s data center group, discusses the soaring demand for AI hardware. He highlights the significant supply challenges in GPU production and the competitive strategies companies are using to secure compute resources. The conversation navigates the decision-making process between cloud services and in-house infrastructure, emphasizing the role of open source and the increasing importance of data efficiency. Expect insights on future AI model trends and the cost implications of compute.


