

Guido Appenzeller
Infra partner at a16z. Expert in computer science and software development.
Top 5 podcasts with Guido Appenzeller
Ranked by the Snipd community

942 snips
May 22, 2025 • 36min
What Is an AI Agent?
Guido Appenzeller, a General Partner at a16z, along with partners Matt Bornstein and Yoko Li, tackle the hot topic of AI agents. They discuss the varying definitions and complexities surrounding these agents, questioning if they are merely enhanced LLMs or something more. The conversation dives into how AI agents are reshaping workplace productivity and the intricate challenges of pricing and integrating them into existing workflows. Ultimately, they envision a future where AI agents are as essential as electricity, transforming our daily lives.

244 snips
May 16, 2025 • 45min
Who's Coding Now? AI and the Future of Software Development
Guido Appenzeller, an Infra partner at a16z and a computer science expert, joins fellow partner Matt Bornstein, an AI application specialist, to explore how generative AI is revolutionizing software development. They discuss the rise of 'prompt-based programming' and its impact on developer productivity. The duo delves into the permanence of formal programming languages amidst AI advancements and the complexities of integrating AI into enterprise systems. They also touch on how these changes will reshape coding education and the future landscape of technology.

49 snips
Jul 27, 2023 • 16min
AI Hardware, Explained
Guido Appenzeller, a seasoned infrastructure expert and advisor at A16Z, dives into the evolving role of hardware in AI. He breaks down the essentials of GPUs and TPUs, revealing their significance in today’s AI landscape. The discussion also touches on NVIDIA's market position versus emerging competitors and the importance of software optimizations. Appenzeller examines the nuances of Moore's Law and its implications for future performance and power demands in hardware, setting the stage for deeper explorations in upcoming segments.

47 snips
Aug 2, 2023 • 22min
Chasing Silicon: The Race for GPUs
Guido Appenzeller, a seasoned infrastructure expert and former CTO at Intel’s data center group, discusses the soaring demand for AI hardware. He highlights the significant supply challenges in GPU production and the competitive strategies companies are using to secure compute resources. The conversation navigates the decision-making process between cloud services and in-house infrastructure, emphasizing the role of open source and the increasing importance of data efficiency. Expect insights on future AI model trends and the cost implications of compute.

42 snips
Aug 7, 2023 • 14min
The True Cost of Compute
In this discussion, Guido Appenzeller, an A16Z Special Advisor and infrastructure aficionado with a rich background at Intel, dives deep into the economic realities of AI hardware. He reveals the staggering costs of training models and questions the sustainability of current compute investments. The conversation also highlights the distinct financial dynamics between training and inference. As AI matures, Appenzeller emphasizes that efficient hardware is crucial, setting the stage for future innovations in technology.