Gerald Shulman
Professor of Medicine and Cellular & Molecular Physiology at Yale; co-director of the Yale Diabetes Research Center. His research focuses on insulin resistance and type 2 diabetes, using advanced technologies to analyze metabolic flux within cells.
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168 snips
Nov 21, 2022 • 2h 7min
A masterclass on insulin resistance—mechanisms and implications | Gerald Shulman, M.D., Ph.D. (#140 rebroadcast)
Gerald Shulman, a Yale Professor and Director of the Diabetes Research Center, shares his expertise on insulin resistance and its implications for health. He dives into mechanisms affecting muscle and liver function, the evolutionary role of insulin resistance, and how lifestyle factors like diet and exercise play a significant part. Shulman also highlights the effectiveness of Metformin, linking its action to longevity, while explaining the alarming connections between lipid accumulation and metabolic health.
85 snips
Dec 7, 2020 • 2h 9min
#140 - Gerald Shulman, M.D., Ph.D.: A masterclass on insulin resistance—molecular mechanisms and clinical implications
Gerald Shulman, a Professor at Yale and expert in insulin resistance, shares fascinating insights into the molecular mechanisms behind this condition and its role in chronic diseases like type 2 diabetes. He discusses how diet and exercise influence insulin sensitivity and explains the evolutionary purpose of insulin resistance in survival. The implications of his research on gluconeogenesis and lipid metabolism shed light on metabolic health, while his analysis of Metformin reveals its potential as a longevity agent. A masterclass in understanding metabolism!
