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Francesca Celletti
Senior advisor on obesity in the Department of Nutrition and Food Safety at the World Health Organization who led development of the WHO guideline on GLP-1 therapies and contributed policy and implementation perspectives.
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Dec 17, 2025
• 34min
WHO Guideline on the Use and Indications of GLP-1 Therapies for the Treatment of Obesity in Adults
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Francesca Celletti, a Senior Advisor at WHO focusing on obesity, and Ezekiel Emanuel, a professor at the University of Pennsylvania, dive into the WHO's new guidelines on GLP-1 therapies for obesity treatment. They discuss crucial recommendations, the importance of ongoing data, and the gap in long-term understanding. Concerns about side effects, lifestyle interventions, and equitable access are raised. Both emphasize that while medications are essential, solving obesity requires systemic changes and collaboration.
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