Charles McElwee, Editor of RealClear Pennsylvania, shares insights on the political shifts in Pennsylvania, particularly after the recent Senate race. Frances Collins, former NIH Director, discusses the delicate balance between politics and science during the COVID-19 pandemic, emphasizing the need for trust in healthcare. The conversation also touches on the ICC's arrest warrants for Israeli officials, raising questions about international law biases, as well as the escalating tensions in Ukraine that impact global politics.