In this engaging discussion, Eric W. Dolan, a researcher in the neuroscience of decision-making, and Eleanor Holton, who studies goal commitment, explore fascinating topics. They dive into how our brains can trap us in the sunk cost fallacy, making it hard to let go of failing pursuits. They also unveil a remarkable discovery of lost wheat genes that could revolutionize global food production. Lastly, they introduce cutting-edge wearable technology capable of diagnosing diseases by analyzing sweat—transforming personal health monitoring.