Arthi Rao, a cardiology fellow, and Eric Sosemsky, a vascular medicine cardiologist, dive deep into the complexities of peripheral arterial disease (PAD). They discuss when to suspect PAD and the critical role of the Ankle-Brachial Index (ABI) in diagnosis. The conversation highlights non-surgical management strategies, emphasizing lifestyle changes, medications like cilostazol, and cardiovascular risk management. They also outline when revascularization may be necessary and explore therapy options that can significantly improve patient quality of life.