Eli Holderness, a Research Software Advocate known for his expertise in data science, joins Hannes Lowette, a Principal Consultant and whiskey lover, to discuss the innovative OpenSAFELY initiative. They delve into how this system allows researchers to safely access sensitive patient data through code execution in a secure environment, ensuring privacy. The conversation also covers the creation of EHRQL, a specialized query language for healthcare research, and highlights the ethical challenges of maintaining patient trust while advancing medical research.