
Eleni Gavriilaki, MD
Expert in managing and treating toxicities associated with CAR-T therapy
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Mar 16, 2023 • 14min
Managing and treating toxicities associated with CAR-T therapy: CRS, ICANS & infections
Experts discuss strategies for minimizing cytokine release syndrome (CRS) and immune effect cell associated neurotoxicity syndrome (ICANS) in CAR T cell therapy. They explore treatment approaches for severe and refractory CRS, including the use of medications like anakinera and cetuximab. The podcast also covers the management of toxicities associated with CAR-T therapy, recommendations for managing early and late infections, and the use of GCSE stimulation and intravenous immunoglobulin substitution.