Liam Fedus, a former OpenAI research leader who co-created ChatGPT, and Ekin Doğuş Çubuk, an ex-Google DeepMind head of materials research, discuss their groundbreaking venture, Periodic Labs. They aim to create AI-driven physical labs that connect real-world experiments with AI insights. Key topics include 'experiment-in-the-loop' strategies, measuring robotic success through superconductivity metrics, and the importance of cross-disciplinary teams. They highlight a unique culture prioritizing curiosity and collaboration, aiming to reshape scientific discovery through AI.