Dr. Salim R. Rezaie, a community emergency physician and founder of REBEL EM, joins the discussion on the controversial role of Vitamin C in treating sepsis. They critically analyze a troubling case study involving a 59-year-old woman and delve into the study methodology, discussing the importance of evidence-based medicine. The conversation highlights the potential risks and mortality linked to Vitamin C therapy, urging caution in its use. Salim emphasizes the need for rigorous trials to ensure patient safety and effective treatment.

Dr. Salim Rezaie, a community emergency physician and founder of the critical appraisal blog REBEL EM, dives deep into the impact of tranexamic acid (TXA) in trauma care. He explores a striking motor vehicle collision case, debating TXA’s effectiveness versus traditional treatments. The discussion highlights key studies like CRASH-2 and scrutinizes research methodologies, showing how they influence patient outcomes. Engagingly, they weigh the survival benefits against potential long-term issues, all while adding a splash of humor to the serious topic of emergency medicine.