Dr. Muller, an Epileptologist and medical educator at Yale, joins medical students Charlie Zhao and Sonya Zhou to dissect the critical topic of loss of consciousness. They delve into the neuroanatomy involved, clarifying the roles of alertness and awareness. The trio categorizes disorders behind this phenomenon and emphasizes the importance of thorough clinical evaluations. Additionally, they discuss the complexities of seizures and syncope, the nuances of non-transient cases, and strategies for assessing unconscious patients, offering vital insights for budding medical professionals.