Dr. Chris Carpenter, Vice Chair of Emergency Medicine at Mayo Clinic, shares his expertise in statistics with a festive twist. The discussion hilariously explores the 12 Nerdy Days of Christmas, highlighting common statistical faux pas. From the misunderstood P value to the importance of confidence intervals, Carpenter explains how to safeguard clinical decisions. With a playful debate on holiday movie traditions and whimsical insights into evidence-based medicine, this episode combines holiday cheer with vital statistical empowerment.