Dr. Amber Sandoval, an abdominal wall reconstruction fellow, and Dr. Peter Farron, chief surgical resident at OHSU, dive into the complexities of mesh infections in hernia repair. They discuss risk factors like BMI and smoking, effective source control methods, and the importance of tailored antibiotic strategies. The duo explores mesh properties that influence infection rates and recovery, and the optimal approach to explant—favoring complete removal over partial. A practical treatment algorithm guides listeners through effective management strategies for these challenging cases.