Dr. Amanda Nelson, a rheumatologist and epidemiologist specializing in osteoarthritis and machine learning, joins Dr. Bella Mehta, an academic rheumatologist focused on health disparities and big data, to discuss the transformative role of AI in healthcare. They explore AI's potential in enhancing diagnostic accuracy, patient personalization through digital twins, and the analysis of medical images using deep learning. The conversation navigates the promise of AI in rheumatology while addressing ethical considerations and the need for careful oversight to ensure equitable and effective use.