Neil deGrasse Tyson, a renowned astrophysicist, discusses the latest astronomical discoveries and the pressing ethical considerations of AI development. Political strategist Donna Brazile reflects on recent electoral challenges facing the Democratic Party, emphasizing communication with working-class voters. Andrew Sullivan provides sharp insights into the current political climate, exploring issues like immigration and the Russia-Ukraine conflict. Together, they humorously dissect the complexities of political divides and advocate for compassion during the holiday season.

Donna Brazile and Adam Kinzinger join Bill Maher to discuss the predictions of which Republican candidate will drop out next, the state of the Republican majority in Congress, the Israeli-Arab conflict, and Snoop Dogg's decision to quit pot.

Bill Maher welcomes Albert Brooks, Rob Reiner, Donna Brazile, and Adam Kinzinger. They discuss Thanksgiving traditions, funny high school encounters, homelessness, social media's impact on society, and the negative consequences of constantly sharing political opinions on social media.